CIT: Advanced Education Resources - Part 1

This page contains educational resources and in depth knowledge about CIT, wound healing, and other mechanisms related to CIT. This page is not meant to diagnose or recommend. If you have any questions, please contact us at one our facilities. 


The adult wound healing process

Scar less wound healing is one of the goals of a successful invasive and minimally invasive aesthetic procedure. Although science has helped us understand and the document and the cellular level the wound healing process, scar less wound healing is still unclear.  However, early research places keratinocytes as a significant player in the wound healing process.  

Inflammatory Phase (1-3 days)

This process ensures that enough oxygen and building materials are getting to the wound. This process is relatively quick since the body wants to protect itself from the out environment. New type 3 collagen is initially produced at a rapid rate which is then followed by the tougher type 1 collagen rebuild. 

One of the key elements in this process is macrophages. Without these cells, healing will not occur. Although they are responsible for the removal of debris, they are more responsible for division of the cells. 

Lag and Proliferative Phase (3-5 days)

During this phase, oxygen is very important. However, because of the first phase, access to oxygen has been compromised. Therefore, angiogenesis starts. This process is the formation of new blood vessels which compensates for the earlier limitation. This process can actually be observed as visible point sized nodules on the wound. 

Fibroplastic Phase (5-20 days)

At this point the inflammatory phase has diminished significantly and the body enters a phase that helps rebuild the tissue. 

Maturative Remodeling Phase (28 days - 2 years)

During the initial proliferative phase, tissue was created in a disorganized method. This phase revisits the wound and corrects the collagen to a more oriented and non-traumatized structure.